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When the U.S. Food and Drug Administration approved mifepristone, also known as RU-486 or the abortion pill, for early abortion in September 2000, it was a historic milestone for American women and for all involved in the provision of abortion care. NAF has played a key role in educating health care providers and the public about this abortion option.

Our Early Options medical education program educates and instructs health care professionals, including physicians, nurse-midwives, nurse practitioners, physician assistants, counselors, nurses, and office staff, in the safe and effective administration of mifepristone and misoprostol for early medical abortion.

We educate through conferences, workshops, lectures, and multimedia educational resources. The Early Options program also includes educational materials for women considering a medical abortion.

NAF Protocol for Mifepristone/Misoprostol in Early Abortion

In March 2013, NAF updated its Protocol for Mifepristone/ Misoprostol in Early Abortion (PDF file, 54K).

Clostridial Disease Workshop May 11, 2006

The U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Food and Drug Administration, and National Institutes of Health hosted a Public Workshop on Emerging Clostridial Disease in Atlanta, GA, on May 11, 2006. The workshop summary and transcript were posted on June 20.

Educational Resources and the Early Options Program

Our Early Options medical education program includes numerous multimedia education materials and training opportunities for health care professionals and medical educators about early medical abortion. Topics include medical abortion regimens, patient management, patient counseling, ultrasound, the role of early surgical abortion, administrative and legal issues, and historical context. More

History and Overview

Mifepristone was developed during the early 1980s by a team of researchers working at a French pharmaceutical company. It was first licensed for use in France in 1988, but it wasn't until 12 years later that it was approved in the U.S. Read more about the history and worldwide use of mifepristone


NAF exhibits and sponsors educational sessions at numerous medical conferences to ensure that health care professionals have access to educational resources and information about abortion care. Learn more about reproductive health-focused conferences

Patient Information

Our patient education resource, Making Your Choice: A Woman's Guide to Medical Abortion, describes what to expect during a medical abortion and outlines the similarities and differences between medical and surgical abortion.

Videos are available in English and Spanish.

Brochures are available in:

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Early Options CME. Earn CME credits through our online training program on medical abortion.

Fast Facts about Mifepristone. How does mifepristone work?  How long does it take?  What are the side effects?  Find answers to frequently asked questions about medical abortion.

clinicians for choice. Clinicians Fighting to Keep Reproductive Choice a Reality. view site.
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